Saul Weprin (1927 - 1994) was an American attorney and politician. He was a member of the New York State Assembly and served as its Speaker from December 1991 until his death in 1994.

Weprin was born to Jewish immigrants in Brooklyn and graduated from Brooklyn Law School in 1951, in the late 1950’s he became president of his co-op apartment board in Hollis, Queens, and in 1962 he became Democratic leader of the 24th Assembly District. In 1971, Weprin won in a run for the New York State Assembly and was re-elected many times remaining in the Assembly until he died in 1994. Weprin was an opponent of the death penalty and a supporter of abortion rights. He pushed the first gay rights bill through the Assembly, sought to increase state aid for schools in New York, and defended the state's Medicaid and welfare programs against cuts proposed by the Republican-controlled Senate.